To investigate the axial compression behavior of high-strength concrete columns confined by ultra-high-strength spiral stirrup, 32 specimens were designed and manufactured with the spiral stirrup strength reinforcement, spiral stirrup ratio and concrete strength as the variation parameters. The results show that the ultra-high strength spiral stirrup has a longer elastic stress stage, which can effectively overcome the high brittleness problem of high-strength concrete, and can also ensure that the plastic deformation of high-strength concrete under compression is more than 3%. The peak stress, peak strain and axial compressive ductility coefficient of ultra-high strength (1774MPa) spiral stirrup confined concrete are 1.4, 4.4 and 1.6 times that of ordinary strength (432MPa) spiral stirrup confined concrete, respectively. A comparative analysis was conducted on five existing models for predicting peak stress and strain in confined concrete. The results indicated that the Zheng model exhibited the most accurate prediction for peak stress in ultra-high-strength concrete confined by spiral stirrup. However, all models demonstrated significant deviations in their predictions of peak strain.