To improve the scour resistance of no-fines concrete base material and reveal the attenuation of strength and modulus under different scouring conditions, the response surface method was used to determine the optimal mix of no-fines concrete using 7-day unconfined compressive strength, permeability coefficient, and compressive rebound modulus as the evaluation indexes. The scouring test of no-fines concrete was carried out to analyze the effects of scouring time, scouring frequency, and impact force on the scouring resistance and to reveal the attenuation law of strength and modulus of no-fines concrete after different scouring conditions. The results show that the optimal mix ratio of no-fines concrete is gradation Ⅰ, water-cement ratio 0.35, and target porosity 18%. Compared with cement-stabilized gravel, no-fines concrete has better mechanical properties and scour resistance.