Based on the production data from 2022 to 2023 in a typical plant in China and national and industrial statistics from the past three years， a life cycle assessment（LCA） was conducted for cement production. The environmental load of co-processing of municipal solid waste（MSW） in cement kiln was calculated， and the differences in environmental load per unit strength of different cements were compared. Moreover， the uncertainty of the LCA result was evaluated by data quality indicator and Monte Carlo simulation. Compared with conventional production， the integrated environmental load indicator of one ton of clinker was reduced by 7.82% in the co-processing production. Among the four types of cement， Portland cement P·O 52.5 had the highest integrated environmental load indicator， but its environmental load per unit strength was relatively smaller. Compared with the production of Portland cement P·O 42.5 by conventional clinker production， the integrated environmental load indicator of the production of Portland cement P·C 42.5 by co-processing production was reduced by 16.87%.