The adsorption rules of typical lithological manufactured sands to water， methylene blue and polycarboxylate superplasticizer were studied by taking the quartzite， limestone， granite and basalt as research objects. The adsorption characteristics of manufactured sands were analyzed by Zeta potential， adsorption-desorption isotherm and mercury intrusion curve. The results show that the adsorptions of water and methylene blue on basalt manufactured sand are significantly higher than those on other lithological manufactured sands due to its larger specific surface area and higher porosity. And the adsorption capacity of basalt manufactured sand is increased significantly with the increase of stone powder content. The double electric layer formed by the surface negative charges of stone powder and cations in solution can adsorb superplasticizer molecules. The adsorption ratio of polycarboxylate superplasticizer by stone powders is shown as follows： basalt stone powder>limestone stone powder>granite stone powder>quartzite stone powder. With the coupling effect of electric double layer adsorption and physical adsorption， the adsorption ratio of basalt manufactured sand for polycarboxylate superplasticizer is significantly higher than those of other lithological manufactured sands.