A three point bending repeated loading test was carried out on semi circular asphalt mixture with crumb rubber modified by warm mixing (CR WMA) and hot mixing (CR HMA), which was subjected to salt solution freeze thaw cycles and water solution freeze thaw cycles. At the same time, the cracking characteristics were studied by digital image correlation (DIC) technique. The results show that both the horizontal strain (EXX) and the damage variable defined by full field horizontal strain can reflect the cracking resistance of CR WMA and CR HMA under the fatigue load. The fatigue cracking resistance of CR WMA and CR HMA decreases with the increase of salt solution freeze thaw cycles and water solution freeze thaw cycles. And the effect of salt solution freeze thaw cycles is greater than that of water solution freeze thaw cycles. For both salt solution freeze thaw cycles and water solution freeze thaw cycles, the fatigue cracking resistance of CR WMA is better than that of CR HMA.