The mechanism of dissolution reaction of cement clinker silicate minerals by salicylic acid methanol(SAM) has been investigated. Crystal product made from dissolution of cement clinker by mixing it with sufficient SAM was extracted and cultured. XRD single crystal structure analysis was used to identify the monocrystalline product as calcium salicylate(C14H10O4Ca·2H2O), which is classified as the noncentral Cc spatial group of monoclinic crystal system. In the asymmetric unit, Ca was found to be coordinated with six carboxylate O from the salicylic acid and two water molecules O, giving rise to the formation of an eight coordinate octahedral structure. The FTIR spectrum of the crystal showed that a peak at 3487cm-1 appeared to correspond to boned water molecules, and the peak at 3 519cm-1 disappeared, indicating the disappearance of —OH stretching vibration of the carboxyl group. The peak at 1656cm-1 shifted to lower frequency at 1548cm-1 representing the carbonyl CO stretching vibration. In the 13C NMR spectrum of the crystal, the benzene ring C δ was largely the same as that of salicylic acid. The C7 δ shifted from 17180 to 17609 because the —OH of the carboxyl group takes part in the combination reaction. In 1H NMR spectroscopy the crystal bound water arises at δ=49500 The results have shown that calcium aluminate and calcium ferroalumnates are inert phases in SAM. Calcium salicylate is here synthesized using the carboxyl groups of salicylic acid and CaO of silicate minerals, then dissolved in methanol. The stoichiometric ratio of salicylic acid to CaO from silicate minerals is 2∶1 When the stoichiometric ratio fell below this value, the product became insoluble in methanol so the case is not adopted for clinker mineral separation.