Based on the idea of gradient functional design, gradient structural concrete based on damping enhancement(GSCDE) was prepared. Damping characteristics, compressive strength, interface microhardness and interface microstructure of GSCDE were investigated by means of free vibration method, compressive strength test, microhardness tester and ESEM, respectively. The results show that with the increase of thickness ratio of damping layer, damping ratio of GSCDE increases, but compressive strength decreases. The degree of damage to the appearance of cube specimens is improved. Damping ratio of GSCDE is more than 396% and compressive strength reaches 550MPa. Compared with single layer high performance concrete(HPC) or single layer high damping concrete(HDC), GSCDE can achieve a better balance between damping and strength. GSCDE can effectively solve the problem of combination damping structure integration of high damping concrete. In interface bonding zone between damping layer and structural layer of GSCDE, interface micro hardness uniformly increases from damping layer to structure layer. Moreover, the two kinds of concretes, damping layer and structural layer, have penetrated each other to form a dense, uniform, and stable whole. Interface bonding zone of GSCDE combines well, and it is beneficial to improve mechanical properties and damping characteristics of GSCDE.