In order to analyze the effect of self healing on fatigue life of 70# base asphalt binder and SBS modified asphalt binder, the dynamic shear rheometer(DSR) was employed to perform the time sweep tests with and without rest periods. The deficiency of the common healing index HI1，HI2，HI3 were analyzed and compared, the applicability of the new index HI4 which was corrected by HI3, was proved in terms of fitting of healing equation. Time sweep tests were used at different damage degree and rest periods to analyze their effects on self healing ability. The results indicate that self healing ability of SBS modified asphalt binders was better than 70# base asphalt binders. With the increase of rest periods, the healing condition of asphalt was getting better and better, but the trend was gradually slowing down. The higher the degree of damage, the more difficult it was to heal in the same rest period.