Based on elastic modulus of concrete considering coupling effects of fatigue loading and freezing thawing cycles(FTCs), the fatigue constitutive model of concrete which subjected to freeze thaw damage and the fatigue constitutive equation of steel bar, the material parameters of each model were set up properly in ANSYS. In order to simulate the fatigue behavior of prestressed concrete bending components under the alternative action of FTCs and fatigue loading,these parameters were modified correspondingly. By comparison, the results show that the numerical simulation of the bending deflection and the upper edge strain is in good agreement with the test, which can provide an effective method for the numerical simulation of the fatigue performance of the prestressed concrete components under FTCs in the practical projects.