Compressive strength development of complex binders containing fly ash and（or） tuff powder were investigated. The results show that the physical filling effect of fly ash and tuff has a more intense influence on the compressive strength development of complex binders at an early hydration age. Compared with fly ash， the tuff particles with special morphology has more significant morphology effect and microaggregate effect at the beginning of the hydration. Under the same other condition， the bigger the specific surface area of tuff powder， the greater the compressive strength of complex binders containing tuff powder. The gap is gradually narrowing between the complex binders containing fly ash and the complex binders containing tuff powder due to the pozzolanic activity of fly ash occurs at the late hydration age. Compared with fly ash， the contribution of the tuff powder to the compressive strength of complex binders is given mostly in the early hydration age.