Using the test machine of electro hydraulic servo fatigue tests have been carried out on concrete and the fatigue life, fatigue strength, fatigue stress and fatigue strain have been measured under tension and compression loading both in the absence and presence of lateral pressure. The variation of concrete fatigue was analyzed based on the test results. Having regression treatment by computer, the concrete S N curve of fatigue life and corresponding expressions were obtained. Meanwhile, the concrete fatigue stress strain curves and fatigue strain life curves have been plotted after data processing. The results show that the fatigue behavior of concrete will decrease under the lateral pressure. With the growth of lateral pressure, the fatigue strength will be reduced and the fatigue strain will become larger.