Six different types of AC20 mineral aggregate gradation are provided with distinct Buton rock mixture, and the pavement performance of Buton rock asphalt mixture was conducted by taking AH 70 road asphalt as basis. The results show that rock mineral in raw materials of Buton rock asphalt has a great impact on the mineral aggregate gradation and pavement performance, and appropriate selection of rock mineral mixture can improve comprehensive pavement performance remarkably. The comprehensive pavement performance is close to that of SBS modified asphalt mixture with 05%10% mixing content(by mass), but it is limited in improving the water sensibility of asphalt mixture. The relationship between the dynamic stability of Buton rock asphalt mixture and rock mineral content occurs in concave curve characteristics, and the influence of rock mineral content variations on the dynamic stability of asphalt mixture is remarkable. The raw material of Buton rock asphalt cannot be added into the matrix asphalt for carrying out Marshall test to determine the raw material content as SBS modifier. The particularity of Buton rock asphalt material should be considered during the mix design, and its rock mineral should be separated from the pure asphalt, and blended independently, or the mineral aggregate gradation of Buton rock asphalt will have a great impact on the performance of rock asphalt mixture.