The influence of P, F and organic impurities on surface morphology and length to diameter ratio of calcium sulfate whiskers in phosphoric acid, hydrofluoric acid and organic solutions were explored, and the effects of these impurities on the growth process of calcium sulfate whiskers were studied.The results show that phosphoric acid has an inhibitory effect on calcium sulfate whisker growth. Hydrofluoric acid makes the diameter of calcium sulfate whiskers greater, which means the diameter increases with increasing HF content. When the mass fraction of HF was 08%, the average diameter and length to diameter ratio of calcium sulfate whiskers are 12μm and 28 respectively. Organics reduces the diameter and length to diameter ratio of calcium sulfate whiskers, but its effect is less than that of hydrofluoric acid. However whiteness of calcium sulfate whisker is reduced with increasing organics content. When the mass fraction of organics is 15%, the length to diameter ratio and whiteness of calcium sulfate whiskers are 12 and 55 respectively.