Municipal solid waste incineration fly ash(MSWIFA) was successfully used as raw material in sintering and preparing calcium sulphoaluminate(CSA) cement in laboratory. Compressive strength and durability of the CSA cement based materials were studied. The results show that compressive strength of CSA cement has the similar developing trend with the control cement Ⅰ which develops fast in early curing age but after 7d it increases slowly; the CSA cement based materials are well in resistance to shrinkage, carbonation, permeability, sulfate attack. The chloride from MSWIFA is immobilized into cement clinker and hydrated products. With hydration progress deepening, part of free chloride could also be fixed in the new hydration products.