Serials experiments were designed to study the effect of rubber aggregate(waste tyre) on compressive strength of normally vibrated concrete and self compacting concrete.The experiential relationship between the reduction rate of compressive strength of concrete and the volume fraction of rubber aggregate was established. Results indicate that addition of rubber aggregate remarkably reduces the compressive strength of concrete. The more the volume fraction of rubber aggregate in concrete is, the higher the reduction rate of compressive strength of concrete is. The reduction rate of compressive strength of normally vibrated concrete is slightly higher than that of self compacting concrete with the same volume fraction of rubber aggregate. The effect of rubber aggregate on reduction of compressive strength of concrete is about the same as that of air pore with the same volume fraction of rubber aggregate. The reduction rate of compressive strength of concrete is 4.5% by addition of rubber aggregate of 1% volume fraction, which can be used as reference to design mix proportion.