In order to solve the problem of excessive air and poor bubble size distribution introduced by polycarboxylate superplasticizer. The process of “eliminating large bubbles and introducing small bubbles” was adopted in this paper, in which polycarboxylate superplasticizer is compounded with different kinds of defoaming agents and air entraining agents. Taking air content, fluidity, strength and pore structure parameters of the mortar as indicators to study the synergistic compatibility between polycarboxylate superplasticizer, defoaming agents and air entraining agents. The results show that the defoaming agent can significantly reduce the content of inferior bubbles introduced by polycarboxylate superplasticizer, improve the strength, but reduce the fluidity of mortar; The air entraining agent can increase the bubble content in the diameter range of 10~300μm, reduce the negative influence of the defoaming agent on the fluidity to improve the working performance of the mortar. Therefore, the process of “eliminating large bubbles and introducing small bubbles” can improve the compressive strength while maintaining the fluidity of mortar. Under the test conditions, the compressive strength of mortar can be increased by 15 MPa for 28 days.